Structure of PDB 7eu9 Chain A Binding Site BS01

Receptor Information
>7eu9 Chain A (length=1078) Species: 1410628 (Lachnospiraceae bacterium ND2006) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NASETRKAYTTKMIPRSHDRMKLLGNFMDYLMDGTPIFFELWNQFGGGID
RDIISGTANKDKISDDLLLAVNWFKVMPINSKPQGVSPSNLANLFQQYSG
SEPDIQAQEYFASNFDTEKHQWKDMRVEYERLLAELQLSRSDMHHDLKLM
YKEKCIGLSLSTAHYITSVMFGTGAKNNRQTKHQFYSKVIQLLEESTQIN
SVEQLASIILKAGDCDSYRKLRIRCSRKGATPSILKIVQDYELGTNHDDE
VNVPSLIANLKEKLGRFEYECEWKCMEKIKAFLASKVGPYYLGSYSAMLE
NALSPIKGMTTKNCKFVLKQIDAKNDIKYENEPFGKIVEGFFDSPYFESD
TNVKWVLHPHHIGESNIKTLWEDLNAIHSKYEEDIASLSEDKKEKRIKVY
QGDVCQTINTYCEEVGKEAKTPLVQLLRYLYSRKDDIAVDKIIDGITFLS
KKHKVEKQKINPVIQKYPSFNFGNNSKLLGKIISPKDKLKHNLKCNRNQV
DNYIWIEIKVLNTKTMRWEKHHYALSSTRFLEEVYYPATSENPPDALAAR
FRTKTNGYEGKPALSAEQIEQIRSAPVGLRKVKKRQMRLEAARQQNLLPR
YTWGKDFNINICKRGNNFEVTLATKVKKKKEKNYKVVLGYAANIVRKNTY
AAIEAHANGDGVIDYNDLPVKPIESGFVTVESQVRDKSYDQLSYNGVKLL
YCKPHVESRRSFLEKYRNGTMKDNRGNNIQIDFMKDFEAIADDETSLYYF
NMKYCKLLQSSIRNHSSQAKEYREEIFELLRDGKLSVLKLSSLSNLSFVM
FKVAKSLIGTYFGHLLKKPKAPPITDEDKQKADPEMFALRLALEEKRLNK
VKSKKEVIANKIVAKALELRDKYGPVLIKGENISDTTKKGKKSSTNSFLM
DWLARGVANKVKEMVMMHQGLEFVEVNPNFTSHQDPFVHKNPENTFRARY
SRCTPSELTEKNRKEILSFLSDKPSKRPTNAYYNEGAMAFLATYGLKKND
VLGVSLEKFKQIMANILHQRSEDQLLFPSRGGMFYLATYKLDADATSVNW
NGKQFWVCNADLVAAYNVGLVDIQKDFK
Ligand information
>7eu9 Chain B (length=43) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
auuuuugugcccaucguuggcacuauuaaggaauggaauauag
......<<<<<.......>>>>>....................
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7eu9 Mechanistic insights into the R-loop formation and cleavage in CRISPR-Cas12i1.
Resolution2.35 Å
Binding residue
(original residue number in PDB)		R12 K13 A14 T16 R22 D356 Q431 K463 Q464 K465 N467 P468 I470 K472 Y473 H497 N498 R503 Y509 W511 H528 S532 S533 T534 R535 K560 T561 K567 L570 I575 I578 G584 L585 K587 V588 K590 R591 R594 R620 T627 S688 Q689 V690 R691 Y695 Q697 Y700 V703 Y707 Y754 Q765 R769 K790 L796 S797 S812 G815 T816 H820 K823 K859 N862 K863 S866 E869 N873 T900 K901 K902 S906 N909 M913 K923 E926
Binding residue
(residue number reindexed from 1)		R6 K7 A8 T10 R16 D350 Q425 K457 Q458 K459 N461 P462 I464 K466 Y467 H491 N492 R497 Y503 W505 H522 S526 S527 T528 R529 K554 T555 K561 L564 I569 I572 G578 L579 K581 V582 K584 R585 R588 R614 T621 S682 Q683 V684 R685 Y689 Q691 Y694 V697 Y701 Y748 Q759 R763 K784 L790 S791 S806 G809 T810 H814 K817 K846 N849 K850 S853 E856 N860 T887 K888 K889 S893 N896 M900 K910 E913
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