Structure of PDB 7ep7 Chain A Binding Site BS01
Receptor Information
>7ep7 Chain A (length=327) Species:
10090
(Mus musculus) [
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GPGSASCLELALEGERLCKSGDCRAGVSFFEAAVQVGTEDLKTLSAIYSQ
LGNAYFYLHDYAKALEYHHHDLTLARTIGDQLGEAKASGNLGNTLKVLGN
FDEAIVCCQRHLDISRELNDKVGEARALYNLGNVYHAKGKSFGCPFPEDV
RNALQAAVDLYEENLSLVTALGDRAAQGRAFGNLGNTHYLLGNFRDAVIA
HEQRLLIAKEFGDKAAERRAYSNLGNAYIFLGEFETASEYYKKTLLLARQ
LKDRAVEAQSCYSLGNTYTLLQDYEKAIDYHLKHLAIAQELKDRIGEGRA
CWSLGNAYTALGNHDQAMHFAEKHLEI
Ligand information
>7ep7 Chain B (length=15) Species:
9606
(Homo sapiens) [
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PDSEPDVNEVRALPQ
Receptor-Ligand Complex Structure
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PDB
7ep7
Promotion of row 1-specific tip complex condensates by Gpsm2-G alpha i provides insights into row identity of the tallest stereocilia.
Resolution
2.6 Å
Binding residue
(original residue number in PDB)
L18 E25 Q60 N63 F66 D90 G93 K96 N100 K106 H121 R136 Y139 R196 N200 N203 R221 R235 R236 N240 N243
Binding residue
(residue number reindexed from 1)
L8 E15 Q50 N53 F56 D80 G83 K86 N90 K96 H111 R126 Y129 R179 N183 N186 R204 R218 R219 N223 N226
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:7ep7
,
PDBe:7ep7
,
PDBj:7ep7
PDBsum
7ep7
PubMed
35687681
UniProt
Q8VDU0
|GPSM2_MOUSE G-protein-signaling modulator 2 (Gene Name=Gpsm2)
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