Structure of PDB 7ek4 Chain A Binding Site BS01

Receptor Information
>7ek4 Chain A (length=168) Species: 27405 (Penaeus japonicus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ASQVRQNYHEDCEASINQINMELYASYVYLSMAYYFERDDVALPGFAKFF
KESSDEEREHAQTFMKYQNKRGGRIVLQQIAAPSMREWGTGLEALQAALD
LEKQVNQSLLELHSTASGNNDPHLTKLLEDEYLEEQVDSIKKIGDMITKL
KRAGPTGLGEYMFDKELN
Ligand information
Ligand IDFE
InChIInChI=1S/Fe/q+3
InChIKeyVTLYFUHAOXGGBS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		[Fe+3]
FormulaFe
NameFE (III) ION
ChEMBL
DrugBankDB13949
ZINC
PDB chain7ek4 Chain A Residue 202 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7ek4 Structural Insights for the Stronger Ability of Shrimp Ferritin to Coordinate with Heavy Metal Ions as Compared to Human H-Chain Ferritin.
Resolution2.3 Å
Binding residue
(original residue number in PDB)		E24 E60 H63
Binding residue
(residue number reindexed from 1)		E22 E57 H60
Annotation score5
Enzymatic activity
Enzyme Commision number 1.16.3.1: ferroxidase.
Gene Ontology
Molecular Function
GO:0004322 ferroxidase activity
GO:0008198 ferrous iron binding
GO:0008199 ferric iron binding
GO:0016491 oxidoreductase activity
GO:0046872 metal ion binding
Biological Process
GO:0006826 iron ion transport
GO:0006879 intracellular iron ion homeostasis
GO:0006880 intracellular sequestering of iron ion
Cellular Component
GO:0005737 cytoplasm

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Cellular Component
External links
PDB RCSB:7ek4, PDBe:7ek4, PDBj:7ek4
PDBsum7ek4
PubMed34360624
UniProtT2B7E1

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