Structure of PDB 7e9c Chain A Binding Site BS01

Receptor Information
>7e9c Chain A (length=94) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HRYKPGTVALREIRRFQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSA
IGALQESVEAYLVSLFEDTNLAAIHAKRVTIQKKDIKLARRLRG
Ligand information
>7e9c Chain I (length=130) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gagaatcccggtgccgaggccgctcaattggtcgtagacagctctagcac
cgcttaaacgcacgtacgcgctgtcccccgcgttttaaccgccaagggga
ttactccctagtctccaggcacgtgtcaga
Receptor-Ligand Complex Structure
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PDB7e9c Nucleosome binding relinquishes the association of the BAH domain of Orc1 with Sir1
Resolution3.5 Å
Binding residue
(original residue number in PDB)
R40 V46 R63 L65
Binding residue
(residue number reindexed from 1)
R2 V8 R25 L27
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0008823 cupric reductase (NADH) activity
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Biological Process
GO:0006325 chromatin organization
GO:0006355 regulation of DNA-templated transcription
GO:0006878 intracellular copper ion homeostasis
GO:0009060 aerobic respiration
GO:0009303 rRNA transcription
GO:0042790 nucleolar large rRNA transcription by RNA polymerase I
GO:0043935 sexual sporulation resulting in formation of a cellular spore
GO:0045943 positive regulation of transcription by RNA polymerase I
GO:0070911 global genome nucleotide-excision repair
Cellular Component
GO:0000500 RNA polymerase I upstream activating factor complex
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005694 chromosome
GO:0031298 replication fork protection complex
GO:0032991 protein-containing complex
GO:0043505 CENP-A containing nucleosome

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:7e9c, PDBe:7e9c, PDBj:7e9c
PDBsum7e9c
PubMed
UniProtP61830|H3_YEAST Histone H3 (Gene Name=HHT1)

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