Structure of PDB 7dyv Chain A Binding Site BS01

Receptor Information
>7dyv Chain A (length=229) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
STVPRLHRPSLQHFREQFLVPGRPVILKGVADHWPCMQKWSLEYIQEIAG
CRTVPVEVGEWSQTLMTVNEFISKYIVNEPRDVGYLAQHQLFDQIPELKQ
DISIPDYCSLGDGEEEEITINAWFGPQGTISPLHQDPQQNFLVQVMGRKY
IRLYSPQESGALYPHDTHLLHNTSQVDVENPDLEKFPKFAKAPFLSCILS
PGEILFIPVKYWHYVRALDLSFSVSFWWS
Ligand information
Ligand IDMN
InChIInChI=1S/Mn/q+2
InChIKeyWAEMQWOKJMHJLA-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mn+2]
CACTVS 3.341[Mn++]
FormulaMn
NameMANGANESE (II) ION
ChEMBL
DrugBankDB06757
ZINC
PDB chain7dyv Chain A Residue 501 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7dyv 5-Substituted Pyridine-2,4-dicarboxylate Derivatives Have Potential for Selective Inhibition of Human Jumonji-C Domain-Containing Protein 5.
Resolution1.92 Å
Binding residue
(original residue number in PDB)		H321 D323 H400
Binding residue
(residue number reindexed from 1)		H134 D136 H213
Annotation score1
Enzymatic activity
Enzyme Commision number 1.14.11.73: [protein]-arginine 3-hydroxylase.
3.4.-.-
External links
PDB RCSB:7dyv, PDBe:7dyv, PDBj:7dyv
PDBsum7dyv
PubMed37527664
UniProtQ8N371|KDM8_HUMAN Bifunctional peptidase and arginyl-hydroxylase JMJD5 (Gene Name=KDM8)

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