Structure of PDB 7dwm Chain A Binding Site BS01

Receptor Information
>7dwm Chain A (length=218) Species: 261726 (Hapunavirus VP882) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SISEGDDAYIRSLIHFFGNQPDPWGIKDTKSVFIYANQPFRELVGMKNRN
VEGLTDADMDCETAAFADSFQAQDRLVEQGREKKIVLDVHPYANGWRVFT
FTKTPLIMPSGRVAGTIFHGQDLTDTAGRIERAVVELLLNLTEREELVLF
FLLRGRTAKDIAGMLGRSPRTIEHAIERIRNKFGAGNKRELIDMAMSKGY
YSMVPKALFHTQVSMLLK
Ligand information
Ligand IDA1U
InChIInChI=1S/C6H8N2O/c1-4-3-7-6(9)5(2)8-4/h3H,1-2H3,(H,7,9)
InChIKeyAJYKJVCIKQEVCF-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 12.01c1c(C)nc(c(n1)O)C
CACTVS 3.385Cc1cnc(O)c(C)n1
OpenEye OEToolkits 2.0.6Cc1cnc(c(n1)C)O
FormulaC6 H8 N2 O
Name3,5-dimethylpyrazin-2-ol
ChEMBL
DrugBank
ZINCZINC000014448309
PDB chain7dwm Chain A Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7dwm Understanding the mechanism of asymmetric gene regulation determined by the VqmA of vibriophage.
Resolution2.65 Å
Binding residue
(original residue number in PDB)		K28 F41 F71 D89 F102 K104 F119
Binding residue
(residue number reindexed from 1)		K27 F40 F70 D88 F101 K103 F118
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:7dwm, PDBe:7dwm, PDBj:7dwm
PDBsum7dwm
PubMed33895551
UniProtA2I306

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