Structure of PDB 7dsp Chain A Binding Site BS01

Receptor Information
>7dsp Chain A (length=356) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HHMSEATLLSYTKKLLASPPQLSSTDLHDALLVILSLLQKCDTNSDESLS
IYTKVSSFLTALRVTKLDHKAEYIAEAAKAVLRHSDLVDLPPVILDIVGT
GGDGQNTFNVATSAAIVASGIQGLKICKHGGKDLIGTLGCDMFKVNSSTV
PKLWPDNTFMFLLAPFFHHGMGHVSKIRKFLGIPTVFNVLGPLLHPVSHV
NKRILGVYSKELAPEYAKAAALVYPGSETFIVWGHVGLDEVSPIGKTTVW
HIDPKLKTFQLEPSMFGLEEHELSKCASYGPKENARILKEEVLSGKYHLG
DNNPIYDYILMNTAVLYCLSQGHQNWKEGIIKAEESIHSGNALRSLEHFI
DSVSSL
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain7dsp Chain A Residue 401 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7dsp Crystal structures of anthranilate phosphoribosyltransferase from Saccharomyces cerevisiae.
Resolution1.95 Å
Binding residue
(original residue number in PDB)		D258 E259
Binding residue
(residue number reindexed from 1)		D239 E240
Annotation score1
Enzymatic activity
Enzyme Commision number 2.4.2.18: anthranilate phosphoribosyltransferase.
Gene Ontology
Molecular Function
GO:0004048 anthranilate phosphoribosyltransferase activity
GO:0016757 glycosyltransferase activity
Biological Process
GO:0000162 tryptophan biosynthetic process
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7dsp, PDBe:7dsp, PDBj:7dsp
PDBsum7dsp
PubMed33682790
UniProtP07285|TRPD_YEAST Anthranilate phosphoribosyltransferase (Gene Name=TRP4)

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