Structure of PDB 7dpd Chain A Binding Site BS01

Receptor Information
>7dpd Chain A (length=272) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SMNSDQVTLVGQVFESYVSEYHKNDILLILKERDEDAHYPVVVNAMTLFE
TNMEIGEYFNMFPSEVLTIFDSALRRSALTILQSLSQPEAVSMKQNLHAR
ISGLPVCPELVREHIPKTKDVGHFLSVTGTVIRTSLVKVLEFERDYMCNK
CKHVFVIKADFEQYYTFCPPSSCPSLESCDSSKFTCLSGLSSSPTRCRDY
QEIKIQEQVQRLSVGSIPRSMKVILEDDLVDSCKSGDDLTIYGIVMQRWK
PFQQDVRAEVEIVLKANYIQVN
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain7dpd Chain A Residue 300 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7dpd Structural study of the N-terminal domain of human MCM8/9 complex.
Resolution2.55 Å
Binding residue
(original residue number in PDB)		C147 C150 C172 C178
Binding residue
(residue number reindexed from 1)		C148 C151 C173 C179
Annotation score1
Enzymatic activity
Enzyme Commision number 3.6.4.12: DNA helicase.
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005524 ATP binding
Biological Process
GO:0032508 DNA duplex unwinding

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Molecular Function
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Biological Process
External links
PDB RCSB:7dpd, PDBe:7dpd, PDBj:7dpd
PDBsum7dpd
PubMed34043945
UniProtQ9NXL9|MCM9_HUMAN DNA helicase MCM9 (Gene Name=MCM9)

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