Structure of PDB 7doc Chain A Binding Site BS01

Receptor Information
>7doc Chain A (length=39) Species: 64320 (Zika virus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DMYIERAGDITWEKDAEVTGNSPRLDVALDESGDFSLVE
Ligand information
Receptor-Ligand Complex Structure
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PDB7doc 2-Cyanoisonicotinamide Conjugation: A Facile Approach to Generate Potent Peptide Inhibitors of the Zika Virus Protease.
Resolution1.904 Å
Binding residue
(original residue number in PDB)		G82 D83 F84 L86
Binding residue
(residue number reindexed from 1)		G33 D34 F35 L37
Enzymatic activity
Enzyme Commision number 2.1.1.56: mRNA (guanine-N(7))-methyltransferase.
2.1.1.57: methyltransferase cap1.
2.7.7.48: RNA-directed RNA polymerase.
3.4.21.91: flavivirin.
3.6.1.15: nucleoside-triphosphate phosphatase.
3.6.4.13: RNA helicase.
Gene Ontology
Molecular Function
GO:0004252 serine-type endopeptidase activity
Cellular Component
GO:0044423 virion component

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Molecular Function
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Cellular Component
External links
PDB RCSB:7doc, PDBe:7doc, PDBj:7doc
PDBsum7doc
PubMed34055219
UniProtQ32ZE1|POLG_ZIKV Genome polyprotein

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