Structure of PDB 7dl5 Chain A Binding Site BS01

Receptor Information

>7dl5 Chain A (length=144) Species: 243274 (Thermotoga maritima MSB8) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

MVISEKVRKALNDQLNREIYSSYLYLSMATYFDAEGFKGFAHWMKKQAQE
ELTHAMKFYEYIYERGGRVELEAIEKPPSNWNGIKDAFEAALKHEEFVTQ
SIYNILELASEEKDHATVSFLKWFVDEQVEEEDQVREILDLLEK

Ligand information

InChI=1S/Fe/q+3

VTLYFUHAOXGGBS-UHFFFAOYSA-N

SMILES

Software	SMILES
ACDLabs 10.04 CACTVS 3.341 OpenEye OEToolkits 1.5.0	[Fe+3]

Formula

Fe

Name

FE (III) ION

PDB chain

7dl5 Chain A Residue 201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

Global view

Local view

Structure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

PDB	7dl5 A short helix regulates conversion of dimeric and 24-meric ferritin architectures.
Resolution	2.3 Å
Binding residue (original residue number in PDB)	E19 E52 H55
Binding residue (residue number reindexed from 1)	E18 E51 H54
Annotation score	1

Enzymatic activity

Enzyme Commision number

1.16.3.2: bacterial non-heme ferritin.

Gene Ontology

	Molecular Function
GO:0004322	ferroxidase activity
GO:0008198	ferrous iron binding
GO:0008199	ferric iron binding
GO:0046872	metal ion binding

	Biological Process
GO:0006826	iron ion transport
GO:0006879	intracellular iron ion homeostasis
GO:0006880	intracellular sequestering of iron ion

	Cellular Component
GO:0005737	cytoplasm
GO:0005829	cytosol

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component

External links

PDB	RCSB:7dl5, PDBe:7dl5, PDBj:7dl5
PDBsum	7dl5
PubMed	35120932
UniProt	Q9X0L2

[Back to BioLiP]