Structure of PDB 7dic Chain A Binding Site BS01

Receptor Information
>7dic Chain A (length=646) Species: 243273 (Mycoplasmoides genitalium G37) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KKLQGILTLGNKNSGFIRSLDDDKTVYYVHYSNLTGALDGDLVEFCKLDK
PQFGDKFDAAVITILKRARILYAGNFLVDQNEFALEYKIVADNPRFYLTM
IVNPDSIPNNLASNTKIAFQIDEYDPDNNLCKVSVQQVLGNNDDPLINIK
AIMLDNSIVFETNDVVEQHANKLSFDTEEQHKAYRQDLTDLAFVTVDPTT
SKDLADAIYVKTIPTGFVLYVAIADVAHYVNRNSEIDIEAKHKTSSIYLP
GHYVVPMLPEQLSNQLCSLNPAQKRYVVVCEISFDNQGRIKTNKLYPATI
ISKNRFSYDQVNKWLNNKSELNCDETVINSLKAAFTLSDLIQAQRQKRGT
IDLSHKETEIVVDEHYFPIKINFLVHDKAETMIENLMVVANETVAWVLTN
NKIALPYRVHPRPSKKKLQSLIETVGELNITKPQFNLDTVTSSQIASWLN
ENKDNPSYEIFVILLLRTLGKAFYSVNPLMHFSIGSNHYTHFTSPIRRYI
DLTIHRLLWMHLFTPDQFTDNERDQLKQELEKIADTVNDTEIKIINCERN
ANDYLTTLLLSKQIGKTFSGFISAITSFGIFMRMDENNFDGLIKITTIPD
DFFIFEKEKMVLKGRKTNKVYKIGDRLEAKLSEIDFIQKRAILTLI
Ligand information
Receptor-Ligand Complex Structure
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PDB7dic Molecular mechanism of RNase R substrate sensitivity for RNA ribose methylation.
Resolution2.242 Å
Binding residue
(original residue number in PDB)		N90 D276 S280 D282 D285 Y327 Y387 L432 H434 E436 E463 M466 V467 R487 L545 R546 G549 K550 A551 H560 I563 Y568 H570 T572 R576 R628 F657 F660 D669 R719
Binding residue
(residue number reindexed from 1)		N11 D197 S201 D203 D206 Y248 Y308 L353 H355 E357 E384 M387 V388 R408 L466 R467 G470 K471 A472 H481 I484 Y489 H491 T493 R497 R549 F578 F581 D590 R640
Enzymatic activity
Catalytic site (original residue number in PDB) D276 D282 A284 D285 Y387 R576
Catalytic site (residue number reindexed from 1) D197 D203 A205 D206 Y308 R497
Enzyme Commision number 3.1.13.1: exoribonuclease II.
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0004518 nuclease activity
GO:0004527 exonuclease activity
GO:0004540 RNA nuclease activity
GO:0008859 exoribonuclease II activity
Biological Process
GO:0006402 mRNA catabolic process
GO:0016070 RNA metabolic process
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7dic, PDBe:7dic, PDBj:7dic
PDBsum7dic
PubMed33788943
UniProtP47350|RNR_MYCGE Ribonuclease R (Gene Name=rnr)

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