Structure of PDB 7ddm Chain A Binding Site BS01

Receptor Information
>7ddm Chain A (length=259) Species: 513052 (Burkholderia multivorans CGD2) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PASFAALERAAGGRLGVCAIDTATGRRTLHRADERFPFCSTFKAMLGAAV
LAQSVAHPGLLQQRVTYGRSDLVSYSPVTERHVDTGMTVAELCAATIQYS
DSTAANELMKLIGGPAAVTAYARSIGDDTFRLDRWETELNTALPGDLRDT
TTPAAMAASLRVLVLGDALPAAQRAQLIEWLRGNKVGDKRIRAGVPTGWR
VGDKTGTGDYGTTNDAGVLWPPSRAPIVLAVYYTQTRADAKAKDDVIATA
TRIAIATLG
Ligand information
Receptor-Ligand Complex Structure
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PDB7ddm Frameshift mutations in genes encoding PBP3 and PBP4 trigger an unusual, extreme beta-lactam resistance phenotype in Burkholderia multivorans
Resolution1.2 Å
Binding residue
(original residue number in PDB)		R65 R153 D158 T159 R161
Binding residue
(residue number reindexed from 1)		R35 R123 D128 T129 R131
Enzymatic activity
Enzyme Commision number 3.5.2.6: beta-lactamase.
Gene Ontology
Molecular Function
GO:0008800 beta-lactamase activity
Biological Process
GO:0017001 antibiotic catabolic process
GO:0030655 beta-lactam antibiotic catabolic process
GO:0046677 response to antibiotic

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Molecular Function
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Biological Process
External links
PDB RCSB:7ddm, PDBe:7ddm, PDBj:7ddm
PDBsum7ddm
PubMed
UniProtB9BS30

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