Structure of PDB 7d8t Chain A Binding Site BS01

Receptor Information
>7d8t Chain A (length=199) Species: 9606,224324 [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SLAKERQKKDNHNLIERRRRFNINDRIKELGTLIPKSNDPDMRWNKGTIL
KASVDYIRKLQREQQRAKELENRQKKLEHACRHLLLRIQELGIEDFLKVD
LRVAKVLSAERVEGSEKLLKLTLSLGDEERTVVAGIAKYYTPEELVGKKI
VIVANLKPRKIFGIESQGMILAASDGENLSVIVPDRDVKEGAKLSAALE
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7d8t A unique hyperdynamic dimer interface permits small molecule perturbation of the melanoma oncoprotein MITF for melanoma therapy.
Resolution3.201 Å
Binding residue
(original residue number in PDB)		E320 R323
Binding residue
(residue number reindexed from 1)		E16 R19
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000049 tRNA binding
GO:0000166 nucleotide binding
GO:0004825 methionine-tRNA ligase activity
GO:0005524 ATP binding
GO:0046983 protein dimerization activity
Biological Process
GO:0006431 methionyl-tRNA aminoacylation

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Molecular Function
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Biological Process
External links
PDB RCSB:7d8t, PDBe:7d8t, PDBj:7d8t
PDBsum7d8t
PubMed36588115
UniProtO66738;
O75030

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