Structure of PDB 7d50 Chain A Binding Site BS01

Receptor Information

>7d50 Chain A (length=248) Species: 208964 (Pseudomonas aeruginosa PAO1) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

RLPLIGVTACTKQIGLHPYHIAGDKYLRAVVNGAGGLPLIIPALGESIDQ
AALLDSVDGLLFTGSPSNVEPRHYSGPASEPGTLHDSDRDATTLPLVRAA
IDAGIPVLGICRGFQEMNVAFGGSLHQKVHEVGTFMDHREPADQPLEVQY
APRHAMHVQPGGVLAGIGLPSEFQVNSIHGQGVDRLAPGLRVEALAPDGL
VEAISVEGAKAFALGVQWNPEWQVLTNPNYLAIFQAFGKACSKRAGQR

Ligand information

Ligand ID

InChI

InChI=1S/Mg/q+2

InChIKey

JLVVSXFLKOJNIY-UHFFFAOYSA-N

SMILES

Software	SMILES
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Mg+2]
CACTVS 3.341	[Mg++]

Formula

Name

MAGNESIUM ION

PDB chain

7d50 Chain A Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	7d50 Structure and mechanism of the gamma-glutamyl-gamma-aminobutyrate hydrolase SpuA from Pseudomonas aeruginosa.
Resolution	1.77 Å
Binding residue (original residue number in PDB)	H140 H156 S179 H181 E204
Binding residue (residue number reindexed from 1)	H138 H154 S177 H179 E202
Annotation score	1

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0016787	hydrolase activity
GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
GO:0033969	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
GO:0046872	metal ion binding

	Biological Process
GO:0006541	glutamine metabolic process
GO:0006598	polyamine catabolic process
GO:0046203	spermidine catabolic process

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Molecular Function

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Biological Process

External links

PDB	RCSB:7d50, PDBe:7d50, PDBj:7d50
PDBsum	7d50
PubMed	34605433
UniProt	Q9I6J4

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