Structure of PDB 7d2l Chain A Binding Site BS01

Receptor Information
>7d2l Chain A (length=1077) Species: 1410628 (Lachnospiraceae bacterium ND2006) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NASETRKAYTTKMIPRSHDRMKLLGNFMDYLMDGTPIFFELWNQFGGGID
RDIISGTANKDKISDDLLLAVNWFKVMPINSKPQGVSPSNLANLFQQYSG
SEPDIQAQEYFASNFDTEKHQWKDMRVEYERLLAELQLSRSDMHHDLKLM
YKEKCIGLSLSTAHYITSVMFGTGAKNNRQTKHQFYSKVIQLLEESTQIN
SVEQLASIILKAGDCDSYRKLRIRCSRKGATPSILKIVQDYELGTNHDDE
VNVPSLIANLKEKLGRFEYECEWKCMEKIKAFLASKVGPYYLGSYSAMLE
NALSPIKGMTTKNCKFVLKQIDAKNDIKYENEPFGKIVEGFFDSPYFESD
TNVKWVLHPHHIGESNIKTLWEDLNAIHSKYEEDIASLSEDKKEKRIKVY
QGDVCQTINTYCEEVGKEAKTPLVQLLRYLYSRKDDIAVDKIIDGITFLS
KKHKVEKQKINPVIQKYPSFNFGNNSKLLGKIISPKDKLKHNLKCNRNQV
DNYIWIEIKVLNTKTMRWEKHHYALSSTRFLEEVYYPATSENPPDALAAR
FRTKTNGYEGKPALSAEQIEQIRSAPVGLRKVKKRQMRLEAARQQNLLPR
YTWGKDFNINICKRGNNFEVTLATKVKKKKEKNYKVVLGYAANIVRKNTY
AAIEAHANGDGVIDYNDLPVKPIESGFVTVESQVRDKSYDQLSYNGVKLL
YCKPHVESRRSFLEKYRNGTMKDNRGNNIQIDFMKDFEAIADDETSLYYF
NMKYCKLLQSSIRNHSSQAKEYREEIFELLRDGKLSVLKLSSLSNLSFVM
FKVAKSLIGTYFGHLLKKPAPPITDEDKQKADPEMFALRLALEEKRLNKV
KSKKEVIANKIVAKALELRDKYGPVLIKGENISDTTKKGKKSSTNSFLMD
WLARGVANKVKEMVMMHQGLEFVEVNPNFTSHQDPFVHKNPENTFRARYS
RCTPSELTEKNRKEILSFLSDKPSKRPTNAYYNEGAMAFLATYGLKKNDV
LGVSLEKFKQIMANILHQRSEDQLLFPSRGGMFYLATYKLDADATSVNWN
GKQFWVCNADLVAAYNVGLVDIQKDFK
Ligand information
>7d2l Chain B (length=43) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
auuuuugugcccaucguuggcacuauuaaggaauggaauauag
......<<<<<.......>>>>>....................
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7d2l Mechanistic insights into the R-loop formation and cleavage in CRISPR-Cas12i1.
Resolution2.75 Å
Binding residue
(original residue number in PDB)		R12 K13 A14 T16 R22 K463 Q464 K465 N467 P468 K472 Y473 H497 N498 R503 D507 Y509 W511 H528 S532 T534 R535 K560 K567 L570 I575 R579 G584 L585 K587 V588 K590 R591 R594 T627 S688 Q689 Y695 Q697 Y700 V703 Y707 Y754 Q765 R769 S797 S812 G815 T816 H820 K823 K859 N862 K863 S866 E869 N873 T900 K902 S906 N909 M913 K923 M927
Binding residue
(residue number reindexed from 1)		R6 K7 A8 T10 R16 K457 Q458 K459 N461 P462 K466 Y467 H491 N492 R497 D501 Y503 W505 H522 S526 T528 R529 K554 K561 L564 I569 R573 G578 L579 K581 V582 K584 R585 R588 T621 S682 Q683 Y689 Q691 Y694 V697 Y701 Y748 Q759 R763 S791 S806 G809 T810 H814 K817 K845 N848 K849 S852 E855 N859 T886 K888 S892 N895 M899 K909 M913
External links