Structure of PDB 7d1b Chain A Binding Site BS01

Receptor Information
>7d1b Chain A (length=302) Species: 1908690 (Fimbriiglobus ruber) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ARPAKPDFKTFPLDPDRAVKYVQQLCDIGPRISGTPGMVKQQEVLTKHFE
GLGAKVVRQEFKVRQRSQRGAVDMTNLIASWFPDRKARLIVCSHYDTRPA
AHQETDTQNWRKPFASANDGTAGAALMMELAHHMKGVPSNVGVDFVLFDG
EEYILDPGVPGLQEGDKYFFGSEHFANGYTKAKAGLPYRYTGAVLLDLFA
HDGARLAMEGYSLRGAPNLVAELWRVAGWVGAKSFVNERGFDRATDVLDD
HIALNEAGIPAVDVIDFDYKHWHLLSDTPDKISGKQMVDVGNVLLGWIQI
QK
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain7d1b Chain A Residue 801 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7d1b A Unique Carboxylic-Acid Hydrogen-Bond Network (CAHBN) Confers Glutaminyl Cyclase Activity on M28 Family Enzymes.
Resolution1.24 Å
Binding residue
(original residue number in PDB)		D181 E214 H335
Binding residue
(residue number reindexed from 1)		D119 E152 H273
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0004177 aminopeptidase activity
GO:0008270 zinc ion binding
GO:0016603 glutaminyl-peptide cyclotransferase activity
GO:0016746 acyltransferase activity
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:7d1b, PDBe:7d1b, PDBj:7d1b
PDBsum7d1b
PubMed33774034
UniProtA0A225DNX9

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