Structure of PDB 7cxz Chain A Binding Site BS01

Receptor Information
>7cxz Chain A (length=245) Species: 3702 (Arabidopsis thaliana) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MHHHHHHSSGRENLYFQGHMQKLFDTCKKVFADGKSGTVPSQENIEMLRA
VLDEIKPEDVGVNPKMSYFRSTVTGRSPLVTYLHIYACHRFSICIFCLPP
SGVIPLHNHPEMTVFSKLLFGTMHIKSYDWVPDSPQPSSDTRLAKVKVDS
DFTAPCDTSILYPADGGNMHCFTAKTACAVLDVIGPPYSDPAGRHCTYYF
DYPFSSFSVDGVVVAEEEKEGYAWLKEREEKPEDLTVTALMYSGP
Ligand information
Ligand IDFE
InChIInChI=1S/Fe/q+3
InChIKeyVTLYFUHAOXGGBS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		[Fe+3]
FormulaFe
NameFE (III) ION
ChEMBL
DrugBankDB13949
ZINC
PDB chain7cxz Chain A Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7cxz Molecular basis for cysteine oxidation by plant cysteine oxidases from Arabidopsis thaliana.
Resolution1.561 Å
Binding residue
(original residue number in PDB)		H134 H136 H197
Binding residue
(residue number reindexed from 1)		H107 H109 H170
Annotation score1
Enzymatic activity
Enzyme Commision number 1.13.11.20: cysteine dioxygenase.
Gene Ontology
Molecular Function
GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen

View graph for
Molecular Function
External links
PDB RCSB:7cxz, PDBe:7cxz, PDBj:7cxz
PDBsum7cxz
PubMed33207269
UniProtQ8LGJ5|PCO2_ARATH Plant cysteine oxidase 2 (Gene Name=PCO2)

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