Structure of PDB 7cre Chain A Binding Site BS01

Receptor Information
>7cre Chain A (length=72) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GPIITTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEPLEGSEDRI
ITITGTQDQIQNAQYLLQNSVK
Ligand information
Receptor-Ligand Complex Structure
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PDB7cre Nuclear import receptors and hnRNPK mediates nuclear import and stress granule localization of SIRLOIN.
Resolution3.0 Å
Binding residue
(original residue number in PDB)
G400 S401 I403 G404 K405 G406 G407 R414 R433
Binding residue
(residue number reindexed from 1)
G16 S17 I19 G20 K21 G22 G23 R30 R49
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding

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Molecular Function
External links
PDB RCSB:7cre, PDBe:7cre, PDBj:7cre
PDBsum7cre
PubMed34689235
UniProtP61978|HNRPK_HUMAN Heterogeneous nuclear ribonucleoprotein K (Gene Name=HNRNPK)

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