Structure of PDB 7cnu Chain A Binding Site BS01

Receptor Information
>7cnu Chain A (length=86) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DRKAVIKNADMSEDMQQDAVDCATQAMEKYNIEKDIAAYIKKEFDKKYNP
TWHCIVGRNFGSYVTHETKHFIYFYLGQVAILLFKS
Ligand information
Receptor-Ligand Complex Structure
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PDB7cnu Non-canonical phosphorylation of Bmf by p38 MAPK promotes its apoptotic activity in anoikis.
Resolution2.0 Å
Binding residue
(original residue number in PDB)		D12 R60 F62 G63 S64 Y65 V66 T67 H68 T70 F73 Y75 Y77
Binding residue
(residue number reindexed from 1)		D10 R58 F60 G61 S62 Y63 V64 T65 H66 T68 F71 Y73 Y75
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0045505 dynein intermediate chain binding
Biological Process
GO:0007017 microtubule-based process
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005813 centrosome
GO:0005829 cytosol
GO:0005856 cytoskeleton
GO:0005868 cytoplasmic dynein complex
GO:0005874 microtubule
GO:0005875 microtubule associated complex
GO:0005886 plasma membrane
GO:0005929 cilium
GO:0015630 microtubule cytoskeleton
GO:0016020 membrane
GO:0030286 dynein complex
GO:0031475 myosin V complex
GO:0097542 ciliary tip
GO:0097731 9+0 non-motile cilium
GO:0098794 postsynapse
GO:0098978 glutamatergic synapse

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7cnu, PDBe:7cnu, PDBj:7cnu
PDBsum7cnu
PubMed34462553
UniProtQ96FJ2|DYL2_HUMAN Dynein light chain 2, cytoplasmic (Gene Name=DYNLL2)

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