Structure of PDB 7clv Chain A Binding Site BS01

Receptor Information

>7clv Chain A (length=222) Species: 4932 (Saccharomyces cerevisiae)

MSWLFGDKTPTDDANAAVGGQDTTKPKELSLKQSLGFEPNINNIISGPGG
MHVDTARLHPLAGLDKGVEYLDLEEEQLSSLEGSQGLIPSRGWTDDLCYG
TGAVYLLGLGIGGFSGMMQGLQNIPPNSPGKLQLNTVLNHITKRGPFLGN
NAGILALSYNIINSTIDALRGKHDTAGSIGAGALTGALFKSSKGLKPMGY
SSAMVAAACAVWCSVKKRLLEK

Ligand information

>7clv Chain C (length=25) Species: 4932 (Saccharomyces cerevisiae)

MLSLRQSIRFFKPATRTLCSSRYLL

Receptor-Ligand Complex Structure

Structure summary

• PDB: 7clv Solution structure of the voltage-gated Tim23 channel in complex with a mitochondrial presequence peptide.
• Resolution: N/A
• Binding residue (original residue number in PDB): D65 V68 E69 L71 E82
• Binding residue (residue number reindexed from 1): D65 V68 E69 L71 E82

Gene Ontology

Molecular Function

• GO:0005515 protein binding
• GO:0008320 protein transmembrane transporter activity
• GO:0022857 transmembrane transporter activity
• GO:0030943 mitochondrion targeting sequence binding

Biological Process

• GO:0006886 intracellular protein transport
• GO:0015031 protein transport
• GO:0030150 protein import into mitochondrial matrix
• GO:0045039 protein insertion into mitochondrial inner membrane

Cellular Component

• GO:0005739 mitochondrion
• GO:0005743 mitochondrial inner membrane
• GO:0005744 TIM23 mitochondrial import inner membrane translocase complex
• GO:0005758 mitochondrial intermembrane space

External links

• PDB: RCSB:7clv, PDBe:7clv, PDBj:7clv
• PDBsum: 7clv
• PubMed: 33318647
• UniProt: P32897|TIM23_YEAST Mitochondrial import inner membrane translocase subunit TIM23 (Gene Name=TIM23)