Structure of PDB 7cjb Chain A Binding Site BS01
Receptor Information
>7cjb Chain A (length=147) Species:
9606
(Homo sapiens) [
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RPVLRSVNSREPSQVIFCNRSPRVVLPVWLNFDGEPQPYPTLPPGTGRRI
HSYRGHLWLFRDAGTHDGLLVNQTELFVPSLNVDGQPIFANITLPVYTLK
ERCLQVVRSLVKPENYRRLDIVRSLYEDLEDHPNVQKDLERLTQERI
Ligand information
>7cjb Chain D (length=10) Species:
9606
(Homo sapiens) [
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LYYMAPEHLN
Receptor-Ligand Complex Structure
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PDB
7cjb
VHL recognizes hydroxyproline in RIPK1
Resolution
2.8 Å
Binding residue
(original residue number in PDB)
N67 R69 Q73 W88 F91 Y98 P99 R107 R108 I109 H110 S111 Y112 H115 W117
Binding residue
(residue number reindexed from 1)
N8 R10 Q14 W29 F32 Y39 P40 R48 R49 I50 H51 S52 Y53 H56 W58
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:7cjb
,
PDBe:7cjb
,
PDBj:7cjb
PDBsum
7cjb
PubMed
UniProt
P40337
|VHL_HUMAN von Hippel-Lindau disease tumor suppressor (Gene Name=VHL)
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