Structure of PDB 7cj7 Chain A Binding Site BS01

Receptor Information
>7cj7 Chain A (length=286) Species: 1727196 (Methylomonas sp. DH-1) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AFPKRLEYGGHALVWSGDWSAAGARKAIAGAARAGYDYIEIALLDPWQID
VALTKDLLQEYNLRAHASLGLSAATDVTSTDPAIVAKGDELLRKATDVLY
ALGGSELCGVIYCALGKYPGPASRENRANSVAAMQRLADYAADKGINIDL
EVVNRYETNIMNTGLEGLAFLDEVNRPNAFLHLDTYHMNIEENGMAKSVL
AAGDRLGYVHIGESHRGYLGTGNVDFASFFAALKQIDYRGPITFESFSSE
IVDPKLSNTLCVWRNLWHDSDDLAGKALEFIKQRYG
Ligand information
Ligand IDSOL
InChIInChI=1S/C6H12O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3,5-9,11-12H,1-2H2/t3-,5+,6+/m0/s1
InChIKeyBJHIKXHVCXFQLS-OTWZMJIISA-N
SMILES
SoftwareSMILES
CACTVS 3.370OC[C@H](O)[C@@H](O)[C@H](O)C(=O)CO
ACDLabs 12.01O=C(C(O)C(O)C(O)CO)CO
OpenEye OEToolkits 1.7.0C(C(C(C(C(=O)CO)O)O)O)O
OpenEye OEToolkits 1.7.0C([C@@H]([C@H]([C@@H](C(=O)CO)O)O)O)O
CACTVS 3.370OC[CH](O)[CH](O)[CH](O)C(=O)CO
FormulaC6 H12 O6
NameL-sorbose
ChEMBLCHEMBL1615232
DrugBank
ZINCZINC000090225648
PDB chain7cj7 Chain A Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7cj7 Crystal structure of a novel homodimeric l-ribulose 3-epimerase from Methylomonus sp.
Resolution1.695 Å
Binding residue
(original residue number in PDB)		H12 S69 L70 E152 E158 H188 H211 R217 E246 L261
Binding residue
(residue number reindexed from 1)		H11 S68 L69 E151 E157 H187 H210 R216 E245 L260
Annotation score5
Enzymatic activity
Enzyme Commision number 5.1.3.31: D-tagatose 3-epimerase.
Gene Ontology
Molecular Function
GO:0016853 isomerase activity
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:7cj7, PDBe:7cj7, PDBj:7cj7
PDBsum7cj7
PubMed33838083
UniProtA0A172U6X0|LR3E_METSD L-ribulose 3-epimerase (Gene Name=AYM39_05640)

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