Structure of PDB 7ciy Chain A Binding Site BS01

Receptor Information
>7ciy Chain A (length=278) Species: 79261 (Streptomyces castaneoglobisporus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TVRKNQATLTADEKRRFVAAVLELKRSGRYDEFVRTHNEFIMSDTDSGER
TGHRSPSFLPWHRRFLLDFEQALQSVDSSVTLPYWDWSADRTVRASLWAP
DFLGGTGRSTDGRVMDGPFAASTGNWPINVRVDSRTYLRRSLGGSVAELP
TRAEVESVLAISAYDLPPYNSASEGFRNHLEGWRGVNLHGRVHVWVGGQM
ATGVSPNDPVFWLHHAYVDKLWAEWQRRHPDSAYVPTGGTPDVVDLNETM
KPWNTVRPADLLDHTAYYTFDALEHHHH
Ligand information
Ligand IDCU
InChIInChI=1S/Cu/q+2
InChIKeyJPVYNHNXODAKFH-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Cu+2]
CACTVS 3.341[Cu++]
FormulaCu
NameCOPPER (II) ION
ChEMBL
DrugBankDB14552
ZINC
PDB chain7ciy Chain A Residue 302 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7ciy The basicity of an active-site water molecule discriminates between tyrosinase and catechol oxidase activity.
Resolution1.47 Å
Binding residue
(original residue number in PDB)		H38 H54 H63
Binding residue
(residue number reindexed from 1)		H37 H53 H62
Annotation score3
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0016491 oxidoreductase activity
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:7ciy, PDBe:7ciy, PDBj:7ciy
PDBsum7ciy
PubMed34089758
UniProtQ83WS2

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