Structure of PDB 7cio Chain A Binding Site BS01
Receptor Information
>7cio Chain A (length=109) Species:
9606
(Homo sapiens) [
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GSEDLPHHDEKTWNVGSSNRNKAENLLRGKRDGTFLVRESSKQGSYAVSV
VVDGEVKHLVINKTATGYGFAEPYNLYSSLKELVLHYQHTSLVQHNDSLN
VTLAYPVYA
Ligand information
>7cio Chain B (length=8) Species:
9606
(Homo sapiens) [
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GVYVKMPP
Receptor-Ligand Complex Structure
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PDB
7cio
Molecular interactions of the CTLA-4 cytoplasmic region with the phosphoinositide 3-kinase SH2 domains.
Resolution
1.1 Å
Binding residue
(original residue number in PDB)
R631 R649 S651 S652 H669 L670 V671 F681 A682 E683 H706 N707 L710
Binding residue
(residue number reindexed from 1)
R20 R38 S40 S41 H58 L59 V60 F70 A71 E72 H95 N96 L99
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:7cio
,
PDBe:7cio
,
PDBj:7cio
PDBsum
7cio
PubMed
33386150
UniProt
P27986
|P85A_HUMAN Phosphatidylinositol 3-kinase regulatory subunit alpha (Gene Name=PIK3R1)
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