Structure of PDB 7c7e Chain A Binding Site BS01

Receptor Information
>7c7e Chain A (length=142) Species: 585057 (Escherichia coli IAI39) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TDVLQWVLENDYDPRLISAMSEVRNLVEPAIARWAAERATSSDLAQIESA
LNEMIANNQDREAFNEADIRYHEAVLQSVHNPVLQQLSIAISSLQRAVFE
GDEANMPQTLQEHKALFDAIRHQDGDAAEQAALTMIASSTRR
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain7c7e Chain A Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7c7e Structural and Functional Analyses of the Transcription Repressor DgoR From Escherichia coli Reveal a Divalent Metal-Containing D-Galactonate Binding Pocket.
Resolution2.047 Å
Binding residue
(original residue number in PDB)		D146 H150 H195
Binding residue
(residue number reindexed from 1)		D68 H72 H113
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0046872 metal ion binding
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:7c7e, PDBe:7c7e, PDBj:7c7e
PDBsum7c7e
PubMed33224125
UniProtA0A0H3MRW3

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