Structure of PDB 7c3t Chain A Binding Site BS01

Receptor Information
>7c3t Chain A (length=187) Species: 228410 (Nitrosomonas europaea ATCC 19718) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DALHIGLPPFLVQANNEPRVLAAPEARMGYVLELVRANIAADGGPFAAAV
FERDSGLLIAAGTQRVVPGRCSAAHAEILALSLAQAKLDTHDLSADGLPA
CELVTSAEPCVMCFGAVIWSGVRSLVCAARSDDVEAIGFDEGPRPENWMG
GLEARGITVTTGLLRDAACALLREYNACNGVIYNARC
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain7c3t Chain A Residue 201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7c3t Structure guided mutagenesis reveals the substrate determinants of guanine deaminase.
Resolution2.07 Å
Binding residue
(original residue number in PDB)		H77 C112 C115
Binding residue
(residue number reindexed from 1)		H75 C110 C113
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0008270 zinc ion binding
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
GO:0047974 guanosine deaminase activity
Biological Process
GO:0006152 purine nucleoside catabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:7c3t, PDBe:7c3t, PDBj:7c3t
PDBsum7c3t
PubMed34010666
UniProtQ82Y41

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