Structure of PDB 7bys Chain A Binding Site BS01

Receptor Information

>7bys Chain A (length=427)

NQIVSGAAWTDTAGNTIQAHGAGILQVGSTFYWFGEDKSHNSALFKAVSC
YTSSDLVNWSRQNDALSPIAGTMISTSNVVERPKVIFNQKNSEYVMWFHS
DSSNYGAAMVGVATAKTPCGPYTYKGSFKPLGADSRDESIFQDDDSAQTA
YLLYASDNNQNFKISRLDANYYNVTAQVSVMNGATLEAPGIVKHNGEYFL
IASHTSGWAPNPNKWFSASSLAGPWSAQQDIAPSATRTWYSQNAFDLPLG
SNAIYMGDRWRPSLLGSSRYIWYPLDFSSGAPQIVHADVWSVNVQAGTYS
VASGTSYEAENGQRGGSSTILSGSGFSGGKAVGYLGHGGTVTINNVQSNG
GSHWVALYFANGDSTYRNVTVSVNGGPSVLVDQPDSGGGNVVISVPVKLN
LNSGENSITFGSGQSNYAADLDKIIVY

Ligand information

• Ligand ID: CA
• InChI: InChI=1S/Ca/q+2
• InChIKey: BHPQYMZQTOCNFJ-UHFFFAOYSA-N
• SMILES:
  CACTVS 3.341: [Ca++]
  ACDLabs 10.04
  OpenEye OEToolkits 1.5.0: [Ca+2]
• Formula: Ca
• Name: CALCIUM ION
• DrugBank: DB14577
• PDB chain: 7bys Chain A Residue 503

Receptor-Ligand Complex Structure

Structure summary

• PDB: 7bys Unique active-site and subsite features in the arabinogalactan-degrading GH43 exo-beta-1,3-galactanase from Phanerochaete chrysosporium .
• Resolution: 1.4 Å
• Binding residue (original residue number in PDB): E329 E331 S348 K351 D443
• Binding residue (residue number reindexed from 1): E308 E310 S327 K330 D422
• Annotation score: 4

Enzymatic activity

• Enzyme Commision number: 3.2.1.145: galactan 1,3-beta-galactosidase.

Gene Ontology

Molecular Function

• GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds
• GO:0016798 hydrolase activity, acting on glycosyl bonds
• GO:0030246 carbohydrate binding
• GO:0033943 galactan 1,3-beta-galactosidase activity
• GO:0046872 metal ion binding

Biological Process

• GO:0005975 carbohydrate metabolic process

External links

• PDB: RCSB:7bys, PDBe:7bys, PDBj:7bys
• PDBsum: 7bys
• PubMed: 33093171
• UniProt: Q50KB2