Structure of PDB 7brl Chain A Binding Site BS01

Receptor Information
>7brl Chain A (length=426) Species: 10116 (Rattus norvegicus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SDLTVAVVLPLTNTSYPWSWARVGPAVELALARVKARPDLLPGWTVRMVL
GSSENAAGVCSDTAAPLAAVDLKWEHSPAVFLGPGCVYSAAPVGRFTAHW
RVPLLTAGAPALGIGVKDEYALTTRTGPSHVKLGDFVTALHRRLGWEHQA
LVLYADRLGDDRPCFFIVEGLYMRVRERLNITVNHQEFVEGDPDHYPKLL
RAVRRKGRVIYICSSPDAFRNLMLLALNAGLTGEDYVFFHLDVFGQSLKS
AQGLVPQKPWERGDGQDRSARQAFQAAKIITYKEPDNPEYLEFLKQLKLL
ADKKFNFTVEDGLKNIIPASFHDGLLLYVQAVTETLAQGGTVTDGENITQ
RMWNRSFQGVTGYLKIDRNGDRDTDFSLWDMDPETGAFRVVLNYNGTSQE
LMAVSEHKLYWPLGYPPPDVPKCGFD
Ligand information
Receptor-Ligand Complex Structure
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PDB7brl Structural insight into hormone-recognition and transmembrane signaling by the atrial natriuretic peptide receptor
Resolution3.2 Å
Binding residue
(original residue number in PDB)		D62 Y88 R95 R162 F166
Binding residue
(residue number reindexed from 1)		D62 Y88 R95 R162 F166
Enzymatic activity
Enzyme Commision number 4.6.1.2: guanylate cyclase.
Gene Ontology

View graph for
Cellular Component
External links
PDB RCSB:7brl, PDBe:7brl, PDBj:7brl
PDBsum7brl
PubMed
UniProtP18910|ANPRA_RAT Atrial natriuretic peptide receptor 1 (Gene Name=Npr1)

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