Structure of PDB 7bq4 Chain A Binding Site BS01

Receptor Information
>7bq4 Chain A (length=260) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ADLKSLAKRIYEAYLKNFNMNKVKARVILSGPPFVIHDMETLCMAEKTLV
AKLVANNKEAEVRIFHCCQCTSVETVTELTEFAKAIPGFANLDLNDQVTL
LKYGVYEAIFAMLSSVMNKDGMLVAYGNGFITREFLKSLRKPFCDIMEPK
FDFAMKFNALELDDSDISLFVAAIICCGDRPGLLNVGHIEKMQEGIVHVL
RLHLQSNHPDDIFLFPKLLQKMADLRQLVTEHAQLVQIIKKTESDAALHP
LLQEIYRDMY
Ligand information
Receptor-Ligand Complex Structure
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PDB7bq4 PPAR alpha Ligand-Binding Domain Structures with Endogenous Fatty Acids and Fibrates.
Resolution1.62 Å
Binding residue
(original residue number in PDB)		T288 K292 L302 V306 L309 K310 L459 E462
Binding residue
(residue number reindexed from 1)		T80 K84 L94 V98 L101 K102 L251 E254
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004879 nuclear receptor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
Cellular Component
GO:0005634 nucleus

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7bq4, PDBe:7bq4, PDBj:7bq4
PDBsum7bq4
PubMed33205029
UniProtQ07869|PPARA_HUMAN Peroxisome proliferator-activated receptor alpha (Gene Name=PPARA)

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