Structure of PDB 7bq0 Chain A Binding Site BS01

Receptor Information
>7bq0 Chain A (length=270) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MTADLKSLAKRIYEAYLKNFNMNKVKARVILSGKASNNPPFVIHDMETLC
MAEKTLVAKLVANGIQNKEAEVRIFHCCQCTSVETVTELTEFAKAIPGFA
NLDLNDQVTLLKYGVYEAIFAMLSSVMNKDGMLVAYGNGFITREFLKSLR
KPFCDIMEPKFDFAMKFNALELDDSDISLFVAAIICCGDRPGLLNVGHIE
KMQEGIVHVLRLHLQSNHPDDIFLFPKLLQKMADLRQLVTEHAQLVQIIK
KTESDAALHPLLQEIYRDMY
Ligand information
Receptor-Ligand Complex Structure
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PDB7bq0 PPAR alpha Ligand-Binding Domain Structures with Endogenous Fatty Acids and Fibrates.
Resolution1.771 Å
Binding residue
(original residue number in PDB)
K292 L302 N303 Q305 V306 K310 E462 R465 D466
Binding residue
(residue number reindexed from 1)
K94 L104 N105 Q107 V108 K112 E264 R267 D268
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004879 nuclear receptor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
Cellular Component
GO:0005634 nucleus

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:7bq0, PDBe:7bq0, PDBj:7bq0
PDBsum7bq0
PubMed33205029
UniProtQ07869|PPARA_HUMAN Peroxisome proliferator-activated receptor alpha (Gene Name=PPARA)

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