Structure of PDB 7bil Chain A Binding Site BS01

Receptor Information
>7bil Chain A (length=436) Species: 751945 (Thermus oshimai JL-2) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GLSSEQQRAFLAVTQTPHPAHLITGPAGTGKTTLLYALQEFYKGRAVTLA
PTGTAALQARGQTVHSFFRFPARLLRYRHPEDIRPPGPHSPLRKAIEQME
VLILDEVGMVRVDLLEAMDWALRKTRKRLEEPFGGVKVLLLGDTRQLEPV
VPGGEEALYIARTWGGPFFFQAHVWEEVALRVHRLWESQRQREDPLFAEL
LKRLRQGDPQALETLNRAAVRPDGGEEPGTLILTPRRKEADALNLKRLEA
LPGKPLEYQAQVKGEFAETDFPTEAALTLKKGAQVILLRNDPLGEYFNGD
LGWVEDLEAEALAVRLKRNGRRVVIRPFVWEKIVYTYDSEREEIKPQVVG
TFRQVPVRLAWALTVHKAQGLTLDKVHLELGRGLFAHGQLYVALTRVRRL
QDLSLSRPIAPTELLWRPEVEVFETRIQEGIWQKSH
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7bil Structural and functional studies of SF1B Pif1 from Thermus oshimai reveal dimerization-induced helicase inhibition.
Resolution2.21 Å
Binding residue
(original residue number in PDB)		P117 T118 G119 T129 H131 A138 V216 P218 R302 R303 R355 N356 P358 N364 R392 F394 V395 W396 E397 H432 K433 R448 F451
Binding residue
(residue number reindexed from 1)		P51 T52 G53 T63 H65 A72 V150 P152 R236 R237 R289 N290 P292 N298 R326 F328 V329 W330 E331 H366 K367 R382 F385
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0003678 DNA helicase activity
GO:0004386 helicase activity
GO:0016887 ATP hydrolysis activity
GO:0046872 metal ion binding
Biological Process
GO:0000723 telomere maintenance
GO:0006281 DNA repair
GO:0032508 DNA duplex unwinding

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Molecular Function
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Biological Process
External links
PDB RCSB:7bil, PDBe:7bil, PDBj:7bil
PDBsum7bil
PubMed33784404
UniProtK7RJ88

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