Structure of PDB 7bh8 Chain A Binding Site BS01
Receptor Information
>7bh8 Chain A (length=276) Species:
9606
(Homo sapiens) [
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GSHSLKYFHTSVSRPGRGEPRFISVGYVDDTQFVRFDNDAASPRMVPRAP
WMEQEGSEYWDRETRSARDTAQIFRVNLRTLRGYYNQSEAGSHTLQWMHG
CELGPDGRFLRGYEQFAYDGKDYLTLNEDLRSWTAVDTAAQISEQKSNDA
SEAEHQRAYLEDTCVEWLHKYLEKGKETLLHLEPPKTHVTHHPISDHEAT
LRCWALGFYPAEITLTWQQDGEGHTQDTELVETRPAGDGTFQKWAAVVVP
SGEEQRYTCHVQHEGLPEPVTLRWKP
Ligand information
>7bh8 Chain P (length=9) Species:
9606
(Homo sapiens) [
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VMAPRTVLL
Receptor-Ligand Complex Structure
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PDB
7bh8
Mouse and human antibodies bind HLA-E-leader peptide complexes and enhance NK cell cytotoxicity.
Resolution
1.8 Å
Binding residue
(original residue number in PDB)
Y7 H9 E63 A67 I73 N77 Y84 W97 F116 W133 S143 E152 H155 Q156 Y159 W167 Y171
Binding residue
(residue number reindexed from 1)
Y7 H9 E63 A67 I73 N77 Y84 W97 F116 W133 S143 E152 H155 Q156 Y159 W167 Y171
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:7bh8
,
PDBe:7bh8
,
PDBj:7bh8
PDBsum
7bh8
PubMed
35347236
UniProt
P13747
|HLAE_HUMAN HLA class I histocompatibility antigen, alpha chain E (Gene Name=HLA-E)
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