Structure of PDB 7bai Chain A Binding Site BS01

Receptor Information
>7bai Chain A (length=120) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ENKKLLCRKCKALACYTADVRVIEECHYTVLGDAFKECFVSRPHPKPKQF
SSFEKRAKIFCARQNCSHDWGIHVKYKTFEIPVIKIESFVVEDIATGVQT
LYSKWKDFHFEKIPFDPAEM
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7bai A conserved isoleucine in the RNA sensor RIG-I controls immune tolerance to mitochondrial RNA
Resolution3.4 Å
Binding residue
(original residue number in PDB)
C829 H830 F853 K858 G874 K888 W908
Binding residue
(residue number reindexed from 1)
C26 H27 F50 K55 G71 K85 W105
Enzymatic activity
Enzyme Commision number 3.6.4.13: RNA helicase.
External links
PDB RCSB:7bai, PDBe:7bai, PDBj:7bai
PDBsum7bai
PubMed
UniProtO95786|RIGI_HUMAN Antiviral innate immune response receptor RIG-I (Gene Name=RIGI)

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