Structure of PDB 7bah Chain A Binding Site BS01
Receptor Information
>7bah Chain A (length=121) Species:
9606
(Homo sapiens) [
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KENKKLLCRKCKALACYTADVRVIEECHYTVLGDAFKECFVSRPHPKPKQ
FSSFEKRAKIFCARQNCSHDWGIHVKYKTFEIPVIKIESFVVEDIATGVQ
TLYSKWKDFHFEKIPFDPAEM
Ligand information
>7bah Chain C (length=12) [
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gacgcuagcguc
............
Receptor-Ligand Complex Structure
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PDB
7bah
A conserved isoleucine in the RNA sensor RIG-I controls immune tolerance to mitochondrial RNA
Resolution
1.89 Å
Binding residue
(original residue number in PDB)
C829 H830 F853 K858 I875 K888
Binding residue
(residue number reindexed from 1)
C27 H28 F51 K56 I73 K86
Enzymatic activity
Enzyme Commision number
3.6.4.13
: RNA helicase.
External links
PDB
RCSB:7bah
,
PDBe:7bah
,
PDBj:7bah
PDBsum
7bah
PubMed
UniProt
O95786
|RIGI_HUMAN Antiviral innate immune response receptor RIG-I (Gene Name=RIGI)
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