Structure of PDB 7b3k Chain A Binding Site BS01
Receptor Information
>7b3k Chain A (length=55) Species:
9606
(Homo sapiens) [
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DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLV
MPKKK
Ligand information
>7b3k Chain B (length=12) Species:
32630
(synthetic construct) [
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RPRTRLHTHRNR
Receptor-Ligand Complex Structure
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PDB
7b3k
All - d - Enantiomeric Peptide D3 Designed for Alzheimer's Disease Treatment Dynamically Interacts with Membrane-Bound Amyloid-beta Precursors.
Resolution
N/A
Binding residue
(original residue number in PDB)
Y10 E11 H13 V18 E22 D23 K28 I31 I32
Binding residue
(residue number reindexed from 1)
Y10 E11 H13 V18 E22 D23 K28 I31 I32
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Cellular Component
GO:0016020
membrane
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Cellular Component
External links
PDB
RCSB:7b3k
,
PDBe:7b3k
,
PDBj:7b3k
PDBsum
7b3k
PubMed
34739758
UniProt
P05067
|A4_HUMAN Amyloid-beta precursor protein (Gene Name=APP)
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