Structure of PDB 7b1a Chain A Binding Site BS01

Receptor Information
>7b1a Chain A (length=728) Species: 44689 (Dictyostelium discoideum) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ENPIHDRTSDYHKYLKVKQGDSDLFKLTVSDKRYIWYNPDPKERDSYECG
EIVSETSDSFTFKTVDGQDRQVKKDDANQRNPIKFDGVEDMSELSYLNEP
AVFHNLRVRYNQDLIYTYSGLFLVAVNPFKRIPIYTQEMVDIFKGRRRNE
VAPHIFAISDVAYRSMLDDRQNQSLLITGESGAGKTENTKKVIQYLASVA
GRNSGVLEQQILQANPILEAFGNAKTTRNNNSSRFGKFIEIQFNSAGFIS
GASIQSYLLEKSRVVFQSETERNYHIFYQLLAGATAEEKKALHLAGPESF
NYLNQSGCVDIKGVSDSEEFKITRQAMDIVGFSQEEQMSIFKIIAGILHL
GNIKFEKGAGEGAVLKDKTALNAASTVFGVNPSVLEKALMEPRILAGRDL
VAQHLNVEKSSSSRDALVKALYGRLFLWLVKKINNVLCQERKAYFIGVLD
ISGFEIFKVNSFEQLCINYTNEKLQQFFNHHMFKLEQEEYLKEKINWTFI
DFGLDSQATIDLIDGRQPPGILALLDEQSVFPNATDNTLITKLHSHFSKK
NAKYEEPRFSKTEFGVTHYAGQVMYEIQDWLEKNKDPLQQDLELCFKDSS
DNVVTKLFNDPNIASRAKKGANFITVAAQYKEQLASLMATLEAANPHFVR
CIIPNNKQLPAKLEDKVVLDQLRCNGVLEGIRITRKGFPNRIIYADFVPR
DASQKATDAVLKHLEQYRFGITKIFFRA
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain7b1a Chain A Residue 801 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7b1a Unraveling a Force-Generating Allosteric Pathway of Actomyosin Communication Associated with ADP and P i Release.
Resolution2.6 Å
Binding residue
(original residue number in PDB)		T186 S237
Binding residue
(residue number reindexed from 1)		T186 S233
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003774 cytoskeletal motor activity
GO:0005524 ATP binding
GO:0051015 actin filament binding
Cellular Component
GO:0016459 myosin complex

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Molecular Function
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Cellular Component
External links
PDB RCSB:7b1a, PDBe:7b1a, PDBj:7b1a
PDBsum7b1a
PubMed33374308
UniProtP08799|MYS2_DICDI Myosin-2 heavy chain (Gene Name=mhcA)

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