Structure of PDB 7b0f Chain A Binding Site BS01

Receptor Information
>7b0f Chain A (length=721) Species: 71997 (Thermococcus gorgonarius) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MILDTDYITEDGKPVIRIFKKENGEFKIDYDRNFEPYIYALLKDDSAIED
VKKITAERHGTTVRVVRAEKVKKKFLGRPIEVWKLYFTHPQDQPAIRDKI
KEHPAVVDIYEYDIPFAKRYLIDKGLIPMEGDEELKMLAFAIATLYHEGE
EFAEGPILMISYADEEGARVITWKNIDLPYVDVVSTEKEMIKRFLKVVKE
KDPDVLITYNGDNFDFAYLKKRSEKLGVKFILGREGSEPKIQRMGDRFAV
EVKGRIHFDLYPVIRRTINLPTYTLEAVYEAIFGQPKEKVYAEEIAQAWE
TGEGLERVARYSMEDAKVTYELGKEFFPMEAQLSRLVGQSLWDVSRSSTG
NLVEWFLLRKAYERNELAPNKPDERELARRRESYAGGYVKEPERGLWENI
VYLDFRSLYPSIIITHNVSPDTLNREGCEEYDVAPQVGHKFCKDFPGFIP
SLLGDLLEERQKVKKKMKATIDPIEKKLLDYRQRLIKILANSFYGYYGYA
KARWYCKECAESVTAWGRQYIETTIREIEEKFGFKVLYADTDGFFATIPG
ADAETVKKKAKEFLDYINAKLPGLLELEYEGFYKRGFFATKKKYAVIDEE
DKITTRGLKMRDWSEIAKETQARVLEAILKHGDVEEAVRIVKEVTEKLSK
YEVPPEQLVIYQTVISYIVPKAIPFDEFDPAKHKYDAGYYIENQVLPAVE
RILRAFGYRKEDLRYQKTRQV
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7b0f Structural Studies of HNA Substrate Specificity in Mutants of an Archaeal DNA Polymerase Obtained by Directed Evolution.
Resolution2.797 Å
Binding residue
(original residue number in PDB)		D540 T541 D542 K592 Y594 G607 K609 M610 R613
Binding residue
(residue number reindexed from 1)		D540 T541 D542 K592 Y594 G607 K609 M610 R611
Enzymatic activity
Enzyme Commision number 2.7.7.7: DNA-directed DNA polymerase.
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003887 DNA-directed DNA polymerase activity
GO:0004527 exonuclease activity
Biological Process
GO:0006260 DNA replication
GO:0006261 DNA-templated DNA replication
GO:0071897 DNA biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:7b0f, PDBe:7b0f, PDBj:7b0f
PDBsum7b0f
PubMed33302546
UniProtP56689|DPOL_THEGO DNA polymerase (Gene Name=pol)

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