Structure of PDB 7apz Chain A Binding Site BS01

Receptor Information
>7apz Chain A (length=184) Species: 9031 (Gallus gallus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DRRHVLLQAEFYQRSEGPDKAWAQFGFHFDADELFHVELDAAQTVWRLPE
FGRFASFEAQGALQNMAVGKQNLEVMISNSNRSQQDFVTPELALFPAEAV
SLEEPNVLICYADKFWPPVATMEWRRNGAVVSEGVYDSVYYGRPDLLFRK
FSYLPFVPQRGDVYSCAVRHWGAEGPVQRMWEPE
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain7apz Chain A Residue 206 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB7apz CLIP peptide bound to chicken MHC class II molecule (BL-2) from B2 haplotype with a decamer mode of binding
Resolution1.97 Å
Binding residue
(original residue number in PDB)		E39 D41
Binding residue
(residue number reindexed from 1)		E38 D40
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0006955 immune response
GO:0019882 antigen processing and presentation
Cellular Component
GO:0016020 membrane
GO:0042613 MHC class II protein complex

View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7apz, PDBe:7apz, PDBj:7apz
PDBsum7apz
PubMed
UniProtQ4U5Z6

[Back to BioLiP]