Structure of PDB 7acv Chain A Binding Site BS01

Receptor Information
>7acv Chain A (length=307) Species: 1496 (Clostridioides difficile) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
YTVVKNDWKKAVKQLQDGLKNKTISTIKVSFNGNSVGEVTPASSGAKKAD
RDAAAEKLYNLVNTQLDKLGDGDYVDFEVTYNLATQIITKAEAEAVLTKL
QQYNDKVLINSATDTVKGMVSDTQVDSKNVAANPLKVSDMYTIPSAITGS
DDSGYSIAKPTEKTTSLLYGTVGDATAGKAITVDTASNEAFAGNGKVIDY
NKSFKATVQGDGTVKTSGVVLKDASDMAATGTIKVRVTSAKEESIDVDSS
SYISAENLAKKYVFNPKEVSEAYNAIVALQNDGIESDLVQLVNGKYQVIF
YPEGKRL
Ligand information
>7acv Chain C (length=27) Species: 1496 (Clostridioides difficile) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
AKITIKANKLKDLKDYVDDLKTYNNTY
Receptor-Ligand Complex Structure
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PDB7acv Structure and assembly of the S-layer in C. difficile.
Resolution2.4 Å
Binding residue
(original residue number in PDB)
E248 E249 S250 I251 V253 D254 I259 S260 A261 E262 F270 Y279 I282 L285 K301 Y302 Q303 V304 I305 F306 Y307 P308 R312
Binding residue
(residue number reindexed from 1)
E242 E243 S244 I245 V247 D248 I253 S254 A255 E256 F264 Y273 I276 L279 K295 Y296 Q297 V298 I299 F300 Y301 P302 R306
Enzymatic activity
Enzyme Commision number 3.5.1.28: N-acetylmuramoyl-L-alanine amidase.
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