Structure of PDB 7abs Chain A Binding Site BS01
Receptor Information
>7abs Chain A (length=359) Species:
9606
(Homo sapiens) [
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SFEGQMAEYPTISIDRFDRENLRARAYFLSHCHKDHMKGLRAPTLKRRLE
CSLKVYLYCSPVTKELLLTSPKYRFWKKRIISIEIETPTQISLVDEASGE
KEEIVVTLLPAGHCPGSVMFLFQGNNGTVLYTGDFRLAQGEAARMELLHS
GGRVKDIQSVYLDTTFCDPRFYQIPSREECLSGVLELVRSWITRSPYHVV
WLNCKAAYGYEYLFTNLSEELGVQVHVNKLDMFRNMPEILHHLTTDRNTQ
IHACRHPKAEEYFQWSKLPCGITSRNRIPLHIISIKPSTMWFGERSRKTN
VIVRTGESSYRACFSFHSSYSEIKDFLSYLCPVNAYPNVIPVGTTMDKVV
EILKPLCRS
Ligand information
>7abs Chain E (length=4) [
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cagc
Receptor-Ligand Complex Structure
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PDB
7abs
Structural and mechanistic insights into the Artemis endonuclease and strategies for its inhibition.
Resolution
1.97 Å
Binding residue
(original residue number in PDB)
H35 K36 D37 H115 K207 A208 A209 H319
Binding residue
(residue number reindexed from 1)
H33 K34 D35 H113 K205 A206 A207 H317
Enzymatic activity
Enzyme Commision number
3.1.-.-
External links
PDB
RCSB:7abs
,
PDBe:7abs
,
PDBj:7abs
PDBsum
7abs
PubMed
34387696
UniProt
Q96SD1
|DCR1C_HUMAN Protein artemis (Gene Name=DCLRE1C)
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