Structure of PDB 7aaq Chain A Binding Site BS01

Receptor Information
>7aaq Chain A (length=487) Species: 3702 (Arabidopsis thaliana) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VTAFVIMTCIVAAMGGLLFGYDLGISGGVTSMEEFLTKFFPQVESQMKKA
KHDTAYCKFDNQMLQLFTSSLYLAALVASFMASVITRKHGRKVSMFIGGL
AFLIGALFNAFAVNVSMLIIGRLLLGVGVGFANQSTPVYLSEMAPAKIRG
ALNIGFQMAITIGILVANLINYGTSKMAQHGWRVSLGLAAVPAVVMVIGS
FILPDTPNSMLERGKNEEAKQMLKKIRGADNVDHEFQDLIDAVEAAKKVE
NPWKNIMESKYRPALIFCSAIPFFQQITGINVIMFYAPVLFKTLGFGDDA
ALMSAVITGVVNMLSTFVSIYAVDRYGRRLLFLEGGIQMFICQLLVGSFI
GARFGTSGTGTLTPATADWILAFICVYVAGFAWSWGPLGWLVPSEICPLE
IRPAGQAINVSVNMFFTFLIGQFFLTMLCHMKFGLFYFFASMVAIMTVFI
YFLLPETKGVPIEEMGRVWKQHWFWKKYIPEDAIIGG
Ligand information
Ligand IDBGC
InChIInChI=1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5-,6-/m1/s1
InChIKeyWQZGKKKJIJFFOK-VFUOTHLCSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.7.6C(C1C(C(C(C(O1)O)O)O)O)O
CACTVS 3.370OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O
CACTVS 3.370OC[CH]1O[CH](O)[CH](O)[CH](O)[CH]1O
OpenEye OEToolkits 1.7.6C([C@@H]1[C@H]([C@@H]([C@H]([C@@H](O1)O)O)O)O)O
ACDLabs 12.01OC1C(O)C(OC(O)C1O)CO
FormulaC6 H12 O6
Namebeta-D-glucopyranose;
beta-D-glucose;
D-glucose;
glucose
ChEMBLCHEMBL1614854
DrugBankDB02379
ZINCZINC000003833800
PDB chain7aaq Chain A Residue 600 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7aaq Molecular mechanism of sugar transport in plants unveiled by structures of glucose/H + symporter STP10.
Resolution1.81 Å
Binding residue
(original residue number in PDB)		Q177 I184 Q295 N301 N332 G406 W410
Binding residue
(residue number reindexed from 1)		Q157 I164 Q275 N281 N312 G386 W390
Annotation score5
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005354 galactose transmembrane transporter activity
GO:0009679 hexose:proton symporter activity
GO:0015144 carbohydrate transmembrane transporter activity
GO:0015145 monosaccharide transmembrane transporter activity
GO:0015293 symporter activity
GO:0015578 mannose transmembrane transporter activity
GO:0022857 transmembrane transporter activity
Biological Process
GO:0008645 hexose transmembrane transport
GO:0015749 monosaccharide transmembrane transport
GO:0015757 galactose transmembrane transport
GO:0015761 mannose transmembrane transport
GO:0055085 transmembrane transport
GO:0071333 cellular response to glucose stimulus
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7aaq, PDBe:7aaq, PDBj:7aaq
PDBsum7aaq
PubMed34556835
UniProtQ9LT15|STP10_ARATH Sugar transport protein 10 (Gene Name=STP10)

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