Structure of PDB 7a9w Chain A Binding Site BS01

Receptor Information
>7a9w Chain A (length=513) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ASPWRHELLSFDECVSSALKYSTTPKNPSFAMFWDSMGRAMELYYSLRES
PDFNAYRVSRLIHLLHNGLRSTRDQLVKLSRKPDYDSQSFHKEMMNFLCN
SLKDISDDILIGKVSVSGYGATHLLTSFKELSFDDDCIRIWEASKNLSDE
TTSQAFQEPKVVGFMLPLLYAKTRSLTEPNELYNQIIQSKEFIHPNLYSG
LIKVFIKAEDYEKALSLFGQLCEKAEVRNYGYLIETHLSFIGDSKNLTLA
ESFFDKIINDEMPYKIILQVSTVNSFLQNIWKAQNDFDHVYRIWEKAVKF
YGNTVNPGILSSLNNTFFTIFFENYINDNINGFRKLQEIITFYSGVKKID
EPFFNVMLTRASIWHERSIIDFIDKNYTLYHIPRTIISYRILLKSLGSID
NTNNEEILDRWLELVKKLNELGQQYIANADLSALRDATVVWSQSKRDEKV
FSASEDRIELYLKILKRYTPYFRATKQVYRYTTGCAESYPILNEYLSGYS
DLSAEDIPVPQLH
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB7a9w The pentatricopeptide repeat protein Rmd9 recognizes the dodecameric element in the 3'-UTRs of yeast mitochondrial mRNAs.
Resolution2.55 Å
Binding residue
(original residue number in PDB)
Y149 H156 R163 R166 R174 K175 Y178 Y212 H216 F285 H287 R321 N322 G324 Y325 E328 I360 L361 Q362 V363 S364 G401 I402 S404 S405 P445 N448 V449 T452 I480 R483 I484 K487 A522 S525 R528 R606 G610 C611 S614
Binding residue
(residue number reindexed from 1)
Y56 H63 R70 R73 R81 K82 Y85 Y119 H123 F192 H194 R228 N229 G231 Y232 E235 I267 L268 Q269 V270 S271 G308 I309 S311 S312 P352 N355 V356 T359 I387 R390 I391 K394 A429 S432 R435 R480 G484 C485 S488
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003729 mRNA binding
GO:0003730 mRNA 3'-UTR binding
Biological Process
GO:0006413 translational initiation
GO:0009060 aerobic respiration
GO:0030435 sporulation resulting in formation of a cellular spore
GO:0043488 regulation of mRNA stability
GO:0070935 3'-UTR-mediated mRNA stabilization
GO:0090615 mitochondrial mRNA processing
GO:1903108 regulation of mitochondrial transcription
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:7a9w, PDBe:7a9w, PDBj:7a9w
PDBsum7a9w
PubMed33876744
UniProtP53140|RMD9_YEAST RNA-binding protein RMD9, mitochondrial (Gene Name=RMD9)

[Back to BioLiP]