Structure of PDB 7a2z Chain A Binding Site BS01
Receptor Information
>7a2z Chain A (length=59) Species:
9606
(Homo sapiens) [
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GVTLFVALYDYEARTEDDLSFHKGEKFQIVNNTEGDWWLAHSLTTGETGY
IPSNYVAPV
Ligand information
>7a2z Chain B (length=12) Species:
32630
(synthetic construct) [
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VSLARRPLPPLP
Receptor-Ligand Complex Structure
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PDB
7a2z
Crystal structure of the Fyn SH3 domain L112V-S114N-S115T-E121L-R123H mutant in complex with VSL12 at pH 6.0
Resolution
1.14 Å
Binding residue
(original residue number in PDB)
Y91 D100 E116 G117 D118 W119 Y132 P134 N136 Y137
Binding residue
(residue number reindexed from 1)
Y9 D18 E34 G35 D36 W37 Y50 P52 N54 Y55
Enzymatic activity
Enzyme Commision number
2.7.10.2
: non-specific protein-tyrosine kinase.
External links
PDB
RCSB:7a2z
,
PDBe:7a2z
,
PDBj:7a2z
PDBsum
7a2z
PubMed
UniProt
P06241
|FYN_HUMAN Tyrosine-protein kinase Fyn (Gene Name=FYN)
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