Structure of PDB 6zm2 Chain A Binding Site BS01

Receptor Information
>6zm2 Chain A (length=627) Species: 759272 (Thermochaetoides thermophila DSM 1495) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TIQEVRKSLPVYAYRDAFLDAVKEYQVLILVGETGSGKTTQIPQYLHEAG
YTKGNRKIACTQPRRVAAMSVAARVADEMGVRLGHEVGYSIRFEDCTSEK
TILKYMTDGMLLREMVTSPDLADYSCIMIDEAHERTVHTDILLALIKDLT
RARPELRLIISSATLNAEKFSAYFDDAPIFNVPGRVHPVEVYYTSAPESN
YLEAALVTVFQIHATQPEGDILVFLTGQEEIERACERVEEIRRKLGPEII
ALPIYSNMPSEMQAKIFEPTPPGARKVVFSTNIAETSLTIDGIVYVIDSG
YVKENTFSPVGTTGQSTLAVVPCSRAAANQRMGRAGRVKPGKCFRLYTKY
AYLSEMDESPTPEIQRTSLSSVVLQLKALGIDDLLGFDFLDPPPTELLIK
SLNMLYALGALNSAGQLTRVGRQMGEFPTEPMLAKALIAATQEGCVSEVL
TIVSMLGEVGTLFFRPKDKKVHADSARARFTVRDGGDHLTLLNIYNQWVE
AEYSPIWARENFLAQRSLTRARDVRDQLAKLCDRILDGSEASCGGVNNPT
PILRALTAAFFLNAARLNRAGDGYRTLKNNITVYVHPSSVVRGMDPPPKV
IIYHELVVTSKEYVRSVIPVEPRWLSE
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6zm2 The structure of Prp2 bound to RNA and ADP-BeF 3 - reveals structural features important for RNA unwinding by DEAH-box ATPases.
Resolution2.1 Å
Binding residue
(original residue number in PDB)		R352 R353 I379 R380 T395 G397 M398 R401 G515 Q516 Y546 S547 T572 N573 K594 N596 P719 G751 Q818 H877 P878 S879
Binding residue
(residue number reindexed from 1)		R64 R65 I91 R92 T107 G109 M110 R113 G227 Q228 Y255 S256 T281 N282 K303 N305 P428 G460 Q527 H586 P587 S588
Enzymatic activity
Enzyme Commision number 3.6.4.13: RNA helicase.
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0005524 ATP binding

View graph for
Molecular Function
External links
PDB RCSB:6zm2, PDBe:6zm2, PDBj:6zm2
PDBsum6zm2
PubMed33825710
UniProtG0SEG4

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