Structure of PDB 6zkw Chain A Binding Site BS01

Receptor Information
>6zkw Chain A (length=274) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SHSLKYFHTSVSRPGRGEPRFISVGYVDDTQFVRFDNDAASPRMVPRAPW
MEQEGSEYWDRETRSARDTAQIFRVNLRTLRGYYNQSEAGSHTLQWMHGC
ELGPDGRFLRGYEQFAYDGKDYLTLNEDLRSWTAVDTAAQISEQKSNDAS
EAEHQRAYLEDTCVEWLHKYLEKGKETLLHLEPPKTHVTHHPISDHEATL
RCWALGFYPAEITLTWQQDGEHTQDTELVETRPAGDGTFQKWAAVVVPSG
EEQRYTCHVQHEGLPEPVTLRWKP
Ligand information
>6zkw Chain C (length=9) Species: 83332 (Mycobacterium tuberculosis H37Rv) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
RLPAKAPLL
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6zkw Structure-guided stabilization of pathogen-derived peptide-HLA-E complexes using non-natural amino acids conserves native TCR recognition.
Resolution2.26 Å
Binding residue
(original residue number in PDB)		Y7 E63 A67 N77 Y84 W97 H99 F116 S143 K146 E152 Y159 W167 Y171
Binding residue
(residue number reindexed from 1)		Y6 E62 A66 N76 Y83 W96 H98 F115 S142 K145 E151 Y158 W166 Y170
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:6zkw, PDBe:6zkw, PDBj:6zkw
PDBsum6zkw
PubMed35108401
UniProtP13747|HLAE_HUMAN HLA class I histocompatibility antigen, alpha chain E (Gene Name=HLA-E)

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