Structure of PDB 6zhx Chain A Binding Site BS01

Receptor Information
>6zhx Chain A (length=98) Species: 8355 (Xenopus laevis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSS
AVMALQEASEAYLVALFEDTNLAAIHAKRVTIMPKDIQLARRIRGERA
Ligand information
>6zhx Chain I (length=145) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
atcagaatcccggtgccgaggccgctcaattggtcgtagacagctctagc
accgcttaaacgcacgtacgcgctgtcccccgcgttttaaccgccaaggg
gattactccctagtctccaggcacgtgtcagatatatacatcgat
Receptor-Ligand Complex Structure
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PDB6zhx Mechanistic Insights into Regulation of the ALC1 Remodeler by the Nucleosome Acidic Patch.
Resolution2.5 Å
Binding residue
(original residue number in PDB)
Y41 R42 P43 T45 R72 R83 F84 S86 R116 V117 T118 M120
Binding residue
(residue number reindexed from 1)
Y4 R5 P6 T8 R35 R46 F47 S49 R79 V80 T81 M83
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005694 chromosome

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Molecular Function

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Cellular Component
External links
PDB RCSB:6zhx, PDBe:6zhx, PDBj:6zhx
PDBsum6zhx
PubMed33357431
UniProtP84233|H32_XENLA Histone H3.2

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