Structure of PDB 6zew Chain A Binding Site BS01

Receptor Information
>6zew Chain A (length=288) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GRLIYTAGGYFRQSLSYLEAYNPSNGSWLRLADLQVPRSGLAGCVVGGLL
YAVGGRNNSPDGNTDSSALDCYNPMTNQWSPCASMSVPRNRIGVGVIDGH
IYAVGGSHGCIHHSSVERYEPERDEWHLVAPMLTRRIGVGVAVLNRLLYA
VGGFDGTNRLNSAECYYPERNEWRMITPMNTIRSGAGVCVLHNCIYAAGG
YDGQDQLNSVERYDVETETWTFVAPMRHHRSALGITVHQGKIYVLGGYDG
HTFLDSVECYDPDSDTWSEVTRMTSGRSGVGVAVTMEP
Ligand information
Ligand IDQHB
InChIInChI=1S/C7H7N3O/c1-11-6-4-2-3-5-7(6)9-10-8-5/h2-4H,1H3,(H,8,9,10)
InChIKeyBFBZLCUTOUZMLJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.385COc1cccc2nn[nH]c12
OpenEye OEToolkits 2.0.7COc1cccc2c1[nH]nn2
FormulaC7 H7 N3 O
Name7-methoxy-1~{H}-benzotriazole
ChEMBLCHEMBL4879253
DrugBank
ZINC
PDB chain6zew Chain A Residue 710 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6zew Deconstructing Noncovalent Kelch-like ECH-Associated Protein 1 (Keap1) Inhibitors into Fragments to Reconstruct New Potent Compounds.
Resolution1.38 Å
Binding residue
(original residue number in PDB)		Q530 S555
Binding residue
(residue number reindexed from 1)		Q206 S231
Annotation score1
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:6zew, PDBe:6zew, PDBj:6zew
PDBsum6zew
PubMed33818106
UniProtQ9Z2X8|KEAP1_MOUSE Kelch-like ECH-associated protein 1 (Gene Name=Keap1)

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