Structure of PDB 6za2 Chain A Binding Site BS01

Receptor Information
>6za2 Chain A (length=1081) Species: 431947 (Porphyromonas gingivalis ATCC 33277) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QRAMGKTADRSLMASGHWVKIRVDASGVYRLTDEQLRANGFSDPSKVGVF
GYGGGVLPEDLSRITTDDLPPVPVLRQGNALYFYAVGPVTWFYNPAKTTM
EHTVNTYSTHGYYFLSDAAGAPLQMSQYTGGGASAEALIDYYDELMLHEQ
ELYSPKESGRDLYGESFSAVNTRTVKFPLRGNTRSSGELGTVFSYIAKAR
SAGGGREMSLSANGILIFSDPFSMTSNEVSNSYLAGKKRRLYRSTPMNSL
VNELRLDANYSMTGDAVNLDFIEVATQNDLRYDGAPMHIRRFSNLPVLGG
ESCRFVISEVPESLVVLQANSSLTASLVPVKTVGDKTIEFVAPPKGQDRR
TINTFYAVDLSQASAPEILGAVPNQNLHGEEIPDLIIVSTQALLPEADRL
ATYRREKNGLKVLVVLQEQVFNEFSGGTPDATAYRLFAKMFYDRWKANAP
VGETFPMQMLLFGDGAHDNRKVSVAWQKPYLQQTEFLLTFQAVNSTNVNS
YVTDDYFGLLDDQPASVNIGWRNYNMAVGRFPVRTPAEARIAVDKTIRYE
EDRESGAWRIRACFAMPVRAFQDKKKMLETLQSGIILLNYAGHGGPAGWS
DEHLLTLNDIHNFNYKHMPIWITATCEEVFLHEKSGTPIMFSTTRVVYNT
QNEKINGFMLRRMFEKAKDGRYRTMGEIIRSAKQGMLSTVFPDSINQLSF
FLMGDPSVRMNLPTHKVQLTAINGQDPEGQYGTIMLKSLERVALKGKVTD
EKGTFDETFSGKVFLTVFDGRKKMTALEEEGNDLSLVYYDYPNVMYAGIA
EVKDGLFETSFIVPKDVNYSEHEGRINLYAYNESTKAEAMGVDFSIRVQP
GIPDEVTEDNTPPEIISCFLNDSTFRSGDEVNPTPLFMAEVFDLNGINIT
GSGVGHDITLCIDGRADLTYNLNAYFTSSATDAGVGTILFMIPALAEGDH
TARLTVWDIFNNAVHHDFSFRVVDGIAPDVADVILFPNPVRESATFRIFH
NRPGSDLNVVVEIYDFTGRLVNSLPVKTYSSSYGEPIEIKWDLTSKYGVK
IGNGFYLYRCVVNSPGGQTASMAKKMIVVAQ
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain6za2 Chain A Residue 2001 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6za2 Intermolecular latency regulates the essential C-terminal signal peptidase and sortase of the Porphyromonas gingivalis type-IX secretion system.
Resolution3.35 Å
Binding residue
(original residue number in PDB)		E172 E174 L185 D293
Binding residue
(residue number reindexed from 1)		E149 E151 L162 D270
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0008234 cysteine-type peptidase activity
GO:0046872 metal ion binding
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:6za2, PDBe:6za2, PDBj:6za2
PDBsum6za2
PubMed34593635
UniProtB2RGP6

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