Structure of PDB 6yxf Chain A Binding Site BS01

Receptor Information
>6yxf Chain A (length=283) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EFEGRWRVIPHDVLPDWLKDNDFLLHGHRPPMPSFRACFKSIFRIHTETG
NIWTHLLGCVFFLCLGIFYMFRPNISFVAPLQEKVVFGLFFLGAILCLSF
SWLFHTVYCHSEGVSRLFSKLDYSGIALLIMGSFVPWLYYSFYCNPQPCF
IYLIVICVLGIAAIIVSQWDMFATPQYRGVRAGVFLGLGLSGIIPTLHYV
ISEGFLKAATIGQIGWLMLMASLYITGAALYAARIPERFFPGKCDIWFHS
HQLFHIFVVAGAFVHFHGVSNLQEFRFMIGGGC
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain6yxf Chain A Residue 401 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6yxf An automated platform for structural analysis of membrane proteins through serial crystallography.
Resolution3.025 Å
Binding residue
(original residue number in PDB)		H202 H348 H352
Binding residue
(residue number reindexed from 1)		H105 H251 H255
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology

View graph for
Cellular Component
External links
PDB RCSB:6yxf, PDBe:6yxf, PDBj:6yxf
PDBsum6yxf
PubMed34723237
UniProtQ86V24|PAQR2_HUMAN Adiponectin receptor protein 2 (Gene Name=ADIPOR2)

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