Structure of PDB 6yxe Chain A Binding Site BS01

Receptor Information
>6yxe Chain A (length=89) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SITHLPSKVVIQDITMELHCPLCNDWFRDPLMLSCGHNFCEACIQDFWRL
QAKETFCPECKMLCQYNNCTFNPVLDKLVEKIKKLPLLK
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain6yxe Chain A Residue 201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6yxe The RING domain of TRIM69 promotes higher-order assembly.
Resolution2.1 Å
Binding residue
(original residue number in PDB)		C41 C44 C61 C64
Binding residue
(residue number reindexed from 1)		C20 C23 C40 C43
Annotation score4
Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
External links
PDB RCSB:6yxe, PDBe:6yxe, PDBj:6yxe
PDBsum6yxe
PubMed33021497
UniProtQ86WT6|TRI69_HUMAN E3 ubiquitin-protein ligase TRIM69 (Gene Name=TRIM69)

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